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Substance Name: O,O,S-Trimethyl phosphorothioate
RN: 152-20-5
InChIKey: WTUNGUOZHBRADH-UHFFFAOYSA-N

Classification Codes

  • Agricultural Chemical
  • Drug / Therapeutic Agent
  • Insecticide
  • Reproductive Effect

Molecular Formula

  • C3-H9-O3-P-S

Molecular Weight

  • 156.1411
 
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Names and Synonyms

Name of Substance

  • O,O,S-Trimethyl phosphorothioate

Synonyms

  • 4-01-00-01285 (Beilstein Handbook Reference)
  • 8000 Bis HC
  • AI3-29547
  • BRN 1702881
  • CCRIS 5621
  • Dimethylthiomethylphosphate
  • HC7901
  • Methylphosphorothioate((MeO)2(MeS)PO)
  • O,O,S-Triethyl phosphorothioate
  • O,O,S-Trimethyl phosphorothioate
  • O,O,S-Trimethylphosphorothioate
  • Trimethyl phosphorothioate

Systematic Names

  • O,O,S-Trimethyl phosphorothioate
  • Phosphorothioic acid, O,O,S-trimethyl ester

Registry Numbers

CAS Registry Number

  • 152-20-5

System Generated Number

  • 0000152205

Structure Descriptors

InChI

1S/C3H9O3PS/c1-5-7(4,6-2)8-3/h1-3H3

InChIKey

WTUNGUOZHBRADH-UHFFFAOYSA-N

Smiles

COP(=O)(OC)SC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 unreported 25mg/kg (25mg/kg)   Journal of Toxicology and Environmental Health. Vol. 7, Pg. 481, 1981.
chicken LD50 unreported 25mg/kg (25mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Toxicology and Environmental Health. Vol. 7, Pg. 481, 1981.
mouse LD50 intraperitoneal 5mg/kg (5mg/kg)   Actualites Pharmacologiques. Vol. 16, Pg. 7, 1963.
mouse LD50 intravenous 123mg/kg (123mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Developments in Toxicology and Environtal Science. Vol. 8, Pg. 631, 1980.
mouse LD50 oral 38mg/kg (38mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Pesticide Biochemistry and Physiology. Vol. 24, Pg. 251, 1985.
rat LD50 intraperitoneal 51mg/kg (51mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives of Toxicology. Vol. 51, Pg. 221, 1982.
rat LD50 intravenous 45mg/kg (45mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Developments in Toxicology and Environtal Science. Vol. 8, Pg. 631, 1980.
rat LD50 oral 15mg/kg (15mg/kg) BLOOD: HEMORRHAGE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Agricultural and Food Chemistry. Vol. 27, Pg. 463, 1979.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 0.040 (none)   EST
Water Solubility 6.57E+04 mg/L 25 EST
Vapor Pressure 0.206 mm Hg 25 EST
Henry's Law Constant 1.37E-07 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 9.29E-12 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.