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Substance Name: Flurandrenolide [USAN:USP]
RN: 1524-88-5
UNII: 8EUL29XUQT
InChIKey: POPFMWWJOGLOIF-XWCQMRHXSA-N

Note

  • A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)

Molecular Formula

  • C24-H33-F-O6

Molecular Weight

  • 436.5167
 

Classification Codes

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Drug / Therapeutic Agent
  • Glucocorticoid
  • Glucocorticoids
  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Mutation Data

Names and Synonyms

Name of Substance

  • Fludroxycortide [INN]
  • Flurandrenolide
  • Flurandrenolide [USAN:USP]
  • Flurandrenolone

MeSH Heading

  • Flurandrenolone

Synonyms

  • 33379
  • 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with acetone
  • 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxyprogesterone cyclic 16,17-acetal with acetone
  • 6alpha-Fluoro-16alpha-hydroxyhydrocortisone 16,17-acetonide
  • Acetonide of 6alpha-fluoro-16alpha-hydroxyhydrocortisone
  • Alondra-F
  • Cordran
  • Cordran SP
  • Drenison
  • Drocort
  • EINECS 216-196-8
  • Fludrossicortide
  • Fludrossicortide [DCIT]
  • Fludroxicortida
  • Fludroxicortida [INN-Spanish]
  • Fludroxicortidum
  • Fludroxycortide
  • Fludroxycortidum
  • Fludroxycortidum [INN-Latin]
  • Fluorandrenolone
  • Fluorandrenolone acetonide
  • Fluradrenolide
  • Flurandrenolide
  • Flurandrenolone
  • Flurandrenolone acetonide
  • Haelan
  • Haldrone-F
  • HSDB 3084
  • L 33379
  • Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
  • Pregn-4-ene-3,20-dione, 6alpha-fluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
  • Sermaka
  • UNII-8EUL29XUQT

Systematic Names

  • Fludroxycortide
  • Pregn-4-ene-3,20-dione, 6-alpha-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
  • Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-

Registry Numbers

CAS Registry Number

  • 1524-88-5

FDA UNII

  • 8EUL29XUQT

System Generated Number

  • 0001524885

Structure Descriptors

InChI

1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1

InChIKey

POPFMWWJOGLOIF-XWCQMRHXSA-N

Smiles

C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CO)C)O)F

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 251 deg C   EXP
log P (octanol-water) 3.000 (none)   EST
Atmospheric OH Rate Constant 1.36E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.