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Substance Name: Daclizumab [USAN:INN:BAN]
RN: 152923-56-3
UNII: CUJ2MVI71Y

Note

  • An anti-TAC (INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT) monoclonal antibody; immunoglobulin G1 disulfide with human-mouse monoclonal clone 1H4 light chain, dimer; it is used to treat MULTIPLE SCLEROSIS.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Immunologic Factors
  • Immunosuppressive Agents
  • Monoclonal Antibody (Immunosuppressant)

Names and Synonyms

Name of Substance

  • Daclizumab
  • Daclizumab [USAN:INN:BAN]

Synonyms

  • Anti-TAC
  • DAC HYP
  • DAC-HYP
  • Daclizumab
  • Humanized anti-TAC monoclonal antibody comprised of four subunits, two heavy chains and two light chains. All four chains are linked via disulfide bridges. The molecule contains approximately 2% carbohydrate by weight. The antibody belongs to the IgG1 subclass. The DNA sequence is 90% human origin and 10% mouse origin. The humanized anti-TAC is directed to the TAC receptor or high-affinity interleukin 2 receptor. Immunoglobulin G 1 (human-mouse monoclonal clone 1H4 gamma-chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal clone 1H4 light chain, dimer. Molecular weight is approximately 150,000 daltons
  • Immunoglobulin G 1 (human-mouse monoclonal clone 1H4 gamma-chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal clone 1H4 light chain, dimer
  • Ro 24-7375
  • UNII-CUJ2MVI71Y
  • Zenapax
  • Zinbryta

Systematic Name

  • Immunoglobulin G 1 (human-mouse monoclonal clone 1H4 gamma-chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal clone 1H4 light chain, dimer

Registry Numbers

CAS Registry Number

  • 152923-56-3

FDA UNII

  • CUJ2MVI71Y

System Generated Number

  • 0152923563