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Substance Name: Cilomilast [USAN:INN]
RN: 153259-65-5
UNII: 8ATB1C1R6X
InChIKey: CFBUZOUXXHZCFB-OYOVHJISSA-N

Note

  • A selective phosphodiesterase-4 inhibitor for treatment of patients with chronic obstructive pulmonary disease.

Molecular Formula

  • C20-H25-N-O4

Molecular Weight

  • 343.4205
 

Classification Codes

  • Enzyme Inhibitors
  • Phosphodiesterase 4 Inhibitors
  • Phosphodiesterase Inhibitors
  • Phosphodiesterase IV Inhibitor
  • Treatment of Asthma, COPD, Arthritis, Atopic Dermatitis, and Multiple Sclerosis
  • Treatment of Asthma, COPD, Arthritis, Atopic Dermatitis, and Multiple Sclerosis (Phosphodiesterase IV Inhibitor)
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Names and Synonyms

Name of Substance

  • Cilomilast [USAN:INN]

Synonyms

  • Ariflo
  • Cilomilast
  • cis-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-4-cyanocyclohexane-1-carboxylic acid
  • cis-4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid
  • cis-4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexanecarboxylic acid
  • SB 207499
  • SB207499
  • UNII-8ATB1C1R6X

Systematic Name

  • Cyclohexanecarboxylic acid, 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, cis-

Registry Numbers

CAS Registry Number

  • 153259-65-5

FDA UNII

  • 8ATB1C1R6X

System Generated Number

  • 0153259655

Structure Descriptors

InChI

1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20-

InChIKey

CFBUZOUXXHZCFB-OYOVHJISSA-N

Smiles

COc1ccc(cc1OC2CCCC2)[C@@]3(CC[C@H](CC3)C(=O)O)C#N