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Substance Name: Rosiglitazone Maleate [USAN]
RN: 155141-29-0
UNII: KX2339DP44
InChIKey: SUFUKZSWUHZXAV-BTJKTKAUSA-N

Note

  • A peroxisome proliferator-activated receptor gamma agonist; reduces lipid availability, improves insulin action & glucoregulation; Avandia is tradename for the rosiglitazone maleate

Molecular Formula

  • C18-H19-N3-O3-S.C4-H4-O4

Molecular Weight

  • 473.504
 

Classification Codes

  • Antidiabetic
  • Fibrinolytic Agents

Names and Synonyms

Name of Substance

  • Rosiglitazone Maleate [USAN]

Synonyms

  • (+-)-5-(p-(2-(Methyl-2-pyridylamino)ethoxy)benzyl)-2,4-thiazolidinedione maleate (1:1)
  • Avandia
  • BRL 49653-C
  • BRL 49653C
  • BRL-49653-C
  • Rosiglitazone maleate
  • Rosiglitazone XR
  • UNII-KX2339DP44

Systematic Name

  • 2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-, (2Z)-2-butenedioate (1:1)

Mixture Name

  • Avandaryl

Registry Numbers

CAS Registry Number

  • 155141-29-0

FDA UNII

  • KX2339DP44

System Generated Number

  • 0155141290

Molecular Formulas

Molecular Formula

  • C18-H19-N3-O3-S.C4-H4-O4

Molecular Formula Fragments

  • C18-H19-N3-O3-S
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-

InChIKey

SUFUKZSWUHZXAV-BTJKTKAUSA-N

Smiles

c1c(ccc(c1)C[C@@H]1SC(=O)NC1=O)OCCN(C)c1ccccn1.C(\C=C/C(=O)O)(O)=O