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Substance Name: Bimatoprost [USAN:INN:BAN:JAN]
RN: 155206-00-1
UNII: QXS94885MZ
InChIKey: AQOKCDNYWBIDND-FTOWTWDKSA-N

Note

  • A cloprostenol-derived amide that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.

Molecular Formula

  • C25-H37-N-O4

Molecular Weight

  • 415.57
 

Classification Codes

  • Antiglaucoma Agent
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Lowers Intraocular Pressure (IOP) in Patients with Open Angle Glaucoma or Ocular Hypertension (Synthetic Prostamide Analog)

Names and Synonyms

Name of Substance

  • Bimatoprost
  • Bimatoprost [USAN:INN:BAN:JAN]

MeSH Heading

  • Bimatoprost

Synonyms

  • (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide
  • 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-1(alpha(Z),2beta(1E,3S*)3alpha,5alpha))-
  • AGN 192024
  • Bimatoprost
  • Latisse
  • Lumigan
  • UNII-QXS94885MZ

Systematic Names

  • 5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (5Z)-
  • 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-(1alpha(Z),2beta(1E,3S*),3alpha,5alpha))-

Registry Numbers

CAS Registry Number

  • 155206-00-1

FDA UNII

  • QXS94885MZ

Other Registry Number

  • 267244-98-4

System Generated Number

  • 0155206001

Structure Descriptors

InChI

1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1

InChIKey

AQOKCDNYWBIDND-FTOWTWDKSA-N

Smiles

C(\[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C\C=C/CCCC(=O)NCC)=C\[C@H](CCc1ccccc1)O