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Substance Name: Ivabradine [USAN:INN:BAN]
RN: 155974-00-8
UNII: 3H48L0LPZQ
InChIKey: ACRHBAYQBXXRTO-OAQYLSRUSA-N
Note
- A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.
Molecular Formula
- C27-H36-N2-O5
Molecular Weight
- 468.59
Classification Code
- Cardiovascular Agents
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Names and Synonyms
Name of Substance
- Ivabradine
- Ivabradine [USAN:INN:BAN]
MeSH Heading
- Ivabradine
Synonyms
- (S)-3-(3-(((3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
- 3-(3-((((7S)-3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
- 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
- Corlanor
- Corlentor
- Ivabradine
- Procoralan
- S 16257
- S 16257-2
- S-16257
- S-16257-2
- UNII-3H48L0LPZQ
Systematic Name
- 2H-3-Benzazepin-2-one, 3-(3-(((3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, (S)-
Registry Numbers
CAS Registry Number
- 155974-00-8
FDA UNII
- 3H48L0LPZQ
Other Registry Number
- 148870-61-5
System Generated Number
- 0155974008