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Substance Name: Ivabradine [USAN:INN:BAN]
RN: 155974-00-8
UNII: 3H48L0LPZQ
InChIKey: ACRHBAYQBXXRTO-OAQYLSRUSA-N

Note

  • A bradycardic agent; S-16257-2 is the (S)-isomer; S-16260-2 is the (R)-isomer; both (S)- and (R)-isomers have activity.

Molecular Formula

  • C27-H36-N2-O5

Molecular Weight

  • 468.59
 

Classification Code

  • Cardiovascular Agents

Names and Synonyms

Name of Substance

  • Ivabradine
  • Ivabradine [USAN:INN:BAN]

Synonyms

  • (S)-3-(3-(((3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
  • 3-(3-((((7S)-3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
  • 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
  • Corlanor
  • Corlentor
  • Ivabradine
  • Procoralan
  • S 16257
  • S 16257-2
  • S-16257
  • S-16257-2
  • UNII-3H48L0LPZQ

Systematic Name

  • 2H-3-Benzazepin-2-one, 3-(3-(((3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-, (S)-

Registry Numbers

CAS Registry Number

  • 155974-00-8

FDA UNII

  • 3H48L0LPZQ

Other Registry Number

  • 148870-61-5

System Generated Number

  • 0155974008

Structure Descriptors

InChI

1S/C27H36N2O5/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30/h12-14,16,21H,6-11,15,17H2,1-5H3/t21-/m1/s1

InChIKey

ACRHBAYQBXXRTO-OAQYLSRUSA-N

Smiles

N1(C(Cc2c(CC1)cc(c(c2)OC)OC)=O)CCC[N@@](C)C[C@@H]1c2cc(c(cc2C1)OC)OC