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Substance Name: Alvimopan [INN]
RN: 156053-89-3
UNII: Q153V49P3Z
InChIKey: UPNUIXSCZBYVBB-JVFUWBCBSA-N

Note

  • Mu opioid receptor antagonist; intended to treat constipation in patients taking opiates for pain.

Molecular Formula

  • C25-H32-N2-O4

Molecular Weight

  • 424.5378
 

Names and Synonyms

Name of Substance

  • Alvimopan
  • Alvimopan [INN]

Synonyms

  • Alvimopan
  • Alvimopan anhydrous
  • HSDB 7704
  • LY 246736
  • LY246736
  • trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine
  • UNII-Q153V49P3Z

Systematic Name

  • Glycine, N-((2S)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-1-oxo-3-phenylpropyl)-

Registry Numbers

CAS Registry Number

  • 156053-89-3

FDA UNII

  • Q153V49P3Z

Related Registry Number

  • 170098-38-1 (dihydrate)

System Generated Number

  • 0156053893

Structure Descriptors

InChI

1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1

InChIKey

UPNUIXSCZBYVBB-JVFUWBCBSA-N

Smiles

C[C@H]1CN(CC[C@@]1(C)c2cccc(c2)O)C[C@H](Cc3ccccc3)C(=O)NCC(=O)O