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Substance Name: Carbofuran [ANSI:BSI:ISO]
RN: 1563-66-2
UNII: SKF77S6Y67
InChIKey: DUEPRVBVGDRKAG-UHFFFAOYSA-N

Note

  • A cholinesterase inhibitor that is used as a systemic insecticide, an acaricide, and nematocide. (From Merck Index, 11th ed)

Molecular Formula

  • C12-H15-N-O3

Molecular Weight

  • 221.2545
 

Classification Codes

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Anthelmintics
  • Anti-Infective Agents
  • Antinematodal Agents
  • Antiparasitic Agents
  • Avicide
  • Cholinergic Agents
  • Cholinesterase Inhibitors
  • Enzyme Inhibitors
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Nematocide
  • Neurotransmitter Agents
  • Pesticides
  • Reproductive Effect

Superlist Classification Codes

  • Reportable Quantity (RQ) = 10 lb
  • Threshold Planning Quantity (TPQ) = 10/10000 lb
  • TWA 0.1 mg/m3; Not classifiable as a human carcinogen; BEI

Names and Synonyms

Results Name

  • Carbofuran [ANSI:BSI:ISO]

Name of Substance

  • Carbofuran
  • Carbofuran [ANSI:BSI:ISO]

MeSH Heading

  • Carbofuran

Synonyms

  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
  • 2,2-Dimethyl-7-coumaranyl N-methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate
  • 5-17-04-00048 (Beilstein Handbook Reference)
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • AI3-27164
  • BAY 70143
  • Bayer 70143
  • Brifer
  • BRN 1428746
  • C2292-59A
  • Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester
  • Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Carbofuran
  • Carbofurane
  • Caswell No. 160A
  • CCRIS 4017
  • Chinufur
  • Crisfuran
  • Curaterr
  • D 1221
  • Diafuran
  • EINECS 216-353-0
  • ENT 27,164
  • EPA Pesticide Chemical Code 090601
  • FMC 10242
  • Furacarb
  • Furadan
  • Furadan 3G
  • Furadan 4F
  • Furadan F
  • Furadan G
  • HSDB 1530
  • Karbofuranu
  • Karbofuranu [Polish]
  • Kenofuran
  • ME F248
  • Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7
  • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7 [Polish]
  • NIA 10242
  • Niagara 10242
  • Niagara nia-10242
  • NSC 167822
  • OMS 864
  • OMS-864
  • Pillarfuran
  • Sunfuran
  • Terafuran
  • UNII-SKF77S6Y67
  • Yaltox

Systematic Names

  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • Carbofuran
  • Furadan

Superlist Names

  • Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Carbofuran
  • Furadan

Registry Numbers

CAS Registry Number

  • 1563-66-2

FDA UNII

  • SKF77S6Y67

System Generated Number

  • 0001563662

Structure Descriptors

InChI

1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

InChIKey

DUEPRVBVGDRKAG-UHFFFAOYSA-N

Smiles

c12c(CC(O2)(C)C)cccc1OC(NC)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 420ug/kg (0.42mg/kg)   Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
bird - wild LD50 skin 100mg/kg (100mg/kg)   Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
chicken LD50 oral 6300ug/kg (6.3mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
dog LC50 inhalation 52mg/m3 (52mg/m3) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
dog LD50 oral 19mg/kg (19mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
duck LD50 oral 415ug/kg (0.415mg/kg)   Toxicology and Applied Pharmacology. Vol. 22, Pg. 556, 1972.
guinea pig LC50 inhalation 43mg/m3/4H (43mg/m3) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. N5182, Pg. 1967,
mammal (species unspecified) LD50 skin 837mg/kg (837mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(2), Pg. 89, 1988.
mouse LD50 intravenous 450ug/kg (0.45mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#11280,
mouse LD50 oral 2mg/kg (2mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 18, Pg. 793, 1970.
mouse LD50 unreported 5mg/kg (5mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984.
pigeon LD50 oral 1330ug/kg (1.33mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 3160ug/kg (3.16mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit LD50 skin 885mg/kg (885mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 81, 1973.
rabbit LD50 unreported 885mg/kg (885mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 192, 1971.
rat LC50 inhalation 85mg/m3 (85mg/m3) GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
JOM, Journal of Occupational Medicine. Vol. 12, Pg. 16, 1970.
rat LD50 oral 5mg/kg (5mg/kg)   Pesticide Science. Vol. 1, Pg. 117, 1970.
rat LD50 skin 120mg/kg (120mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LD50 unreported 19mg/kg (19mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 23, 1984.
women TDLo oral 1200ug/kg (1.2mg/kg) SKIN AND APPENDAGES (SKIN): SWEATING: OTHER

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Khigiena i Zdraveopazvane. Hygiene and Sanitation. Vol. 24, Pg. 445, 1981.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 151 deg C   EXP
log P (octanol-water) 2.32 (none)   EXP
Water Solubility 320 mg/L 25 EXP
Vapor Pressure 4.85E-06 mm Hg 19 EXP
Henry's Law Constant 3.09E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.60E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.