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Substance Name: Travoprost [USAN:USP:INN:BAN]
RN: 157283-68-6
UNII: WJ68R08KX9
InChIKey: MKPLKVHSHYCHOC-AHTXBMBWSA-N

Note

  • A cloprostenol derivative that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.

Molecular Formula

  • C26-H35-F3-O6

Molecular Weight

  • 500.5505
 

Classification Codes

  • Antiglaucoma Agent
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Treatment of Elevated Intraocular Pressure Associated with Glaucoma (Prostaglandin FP-Receptor Agonist)

Names and Synonyms

Name of Substance

  • Travoprost
  • Travoprost [USAN:USP:INN:BAN]

MeSH Heading

  • Travoprost

Synonyms

  • (((1R)-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester
  • (1R-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-Dihydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester
  • (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3R)-3-hydroxy-4-((alpha,alpha,alpha-trifluoro-m-isopropyl-tolyl)oxy)-1-butenyl)cyclopentyl)-5-heptenoate
  • 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl ester, (1R-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-
  • AL-6221
  • AL6221
  • Izba
  • Travatan
  • Travatan Z
  • Travoprost
  • UNII-WJ68R08KX9

Systematic Name

  • 5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl ester, (5Z)-

Registry Numbers

CAS Registry Number

  • 157283-68-6

FDA UNII

  • WJ68R08KX9

Other Registry Number

  • 207742-69-6

System Generated Number

  • 0157283686

Structure Descriptors

InChI

1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1

InChIKey

MKPLKVHSHYCHOC-AHTXBMBWSA-N

Smiles

CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc2cccc(c2)C(F)(F)F