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Substance Name: Tissue plasminogen activator, MMR 701
RN: 158191-52-7

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect
 
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Names and Synonyms

Synonyms

  • CCRIS 6725
  • MMR 701

Systematic Names

  • MMR 701
  • Tissue plasminogen activator, MMR 701

Registry Numbers

CAS Registry Number

  • 158191-52-7

System Generated Number

  • 0158191527

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LDLo intravenous 77100ug/kg (77.1mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)"

BEHAVIORAL: MUSCLE WEAKNESS
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 21(Suppl,
rat LD50 intravenous 37800ug/kg (37.8mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 21(Suppl,