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Substance Name: Membrane-type matrix metalloproteinase MT1-MMP
RN: 161384-17-4


  • A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.

Molecular Formula

  • Unspecified

Names and Synonyms

MeSH Heading

  • Matrix Metalloproteinase 14


  • Membrane-type matrix metalloproteinase MT1-MMP
  • MMP-14
  • MT-MMP1
  • MT1-MMP

Registry Numbers

CAS Registry Number

  • 161384-17-4

System Generated Number

  • 0161384174