Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Pirlindole hydrochloride
RN: 16154-78-2
UNII: Q89W8I397C
InChIKey: LIFOOCLGAAEVIF-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H18-N2.Cl-H

Molecular Weight

  • 262.782
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Pirlindole hydrochloride

Synonyms

  • 1,10-Trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)indole hydrochloride
  • 1,10-Trimethylene-8-methyltetrahydropyrazino(1,2-a)indole hydrochloride
  • 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1j,k)carbazole hydrochloride
  • EINECS 240-307-9
  • Pirlindole
  • Pirlindole hydrochloride
  • Pirlindon
  • Pirlindon [Spanish]
  • Pyrazidol
  • Pyrazidole
  • UNII-Q89W8I397C

Systematic Names

  • 1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride
  • 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride

Registry Numbers

CAS Registry Number

  • 16154-78-2

FDA UNII

  • Q89W8I397C

Related Registry Number

  • 60762-57-4 (Parent)

System Generated Number

  • 0016154782

Molecular Formulas

Molecular Formula

  • C15-H18-N2.Cl-H

Molecular Formula Fragments

  • C15-H18-N2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H18N2.ClH/c1-10-5-6-14-12(9-10)11-3-2-4-13-15(11)17(14)8-7-16-13;/h5-6,9,13,16H,2-4,7-8H2,1H3;1H

InChIKey

LIFOOCLGAAEVIF-UHFFFAOYSA-N

Smiles

c1cc2c(cc1C)c1c3[C@@H](NCCn23)CCC1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 122mg/kg (122mg/kg)   United States Patent Document. Vol. #4258043,
mouse LD50 intraperitoneal 112mg/kg (112mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Farmakologiya i Toksikologiya Vol. 38, Pg. 5, 1975.
mouse LD50 intravenous 67mg/kg (67mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Farmakologiya i Toksikologiya Vol. 38, Pg. 5, 1975.
mouse LD50 oral 450mg/kg (450mg/kg)   Pharmaceutical Chemistry Journal Vol. 18, Pg. 94, 1984.
mouse LD50 subcutaneous 175mg/kg (175mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Russian Pharmacology and Toxicology Vol. 37, Pg. 192, 1974.
rat LD50 intraperitoneal 185mg/kg (185mg/kg)   Toksikologicheskii Vestnik. Vol. (3), Pg. 17, 1993.
rat LD50 oral 2060mg/kg (2060mg/kg)   Toksikologicheskii Vestnik. Vol. (3), Pg. 17, 1993.