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Substance Name: Amprenavir [USAN:INN:BAN]
RN: 161814-49-9
UNII: 5S0W860XNR
InChIKey: YMARZQAQMVYCKC-OEMFJLHTSA-N

Note

  • Fosamprenavir is a prodrug.

Molecular Formula

  • C25-H35-N3-O6-S

Molecular Weight

  • 505.6325
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antibiotics, Antitubercular
  • Antitubercular Agents
  • Antiviral
  • Antiviral (HIV Protease Inhibitor)
  • Antiviral Agents
  • Enzyme Inhibitors
  • HIV Protease Inhibitors
  • Protease Inhibitors
  • Viral Protease Inhibitors

Names and Synonyms

Name of Substance

  • Amprenavir
  • Amprenavir [USAN:INN:BAN]

Synonyms

  • (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate
  • (3S)-Tetrahydro-3-furyl ((alphaS)-alpha-((1R-1-hydroxy-2-(N(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate
  • (3S-(3R*(1R*,2S*)))-(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl) tetrahydro-3-furanyl carbamate
  • 141W94
  • Agenerase
  • Amprenavir
  • APV
  • DRG-0258
  • HSDB 7157
  • KVX-478
  • Tetrahydro-3-furyl N-(3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxypropyl)carbamate
  • UNII-5S0W860XNR
  • Vertex VX478
  • VX 478
  • VX-478

Systematic Names

  • Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S)-tetrahydro-3-furanyl ester
  • Carbamic acid, (3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, tetrahydro-3-furanyl ester, (3S-(3R*(1S*,2R*)))-

Registry Numbers

CAS Registry Number

  • 161814-49-9

FDA UNII

  • 5S0W860XNR

System Generated Number

  • 0161814499

Structure Descriptors

InChI

InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1

InChIKey

YMARZQAQMVYCKC-OEMFJLHTSA-N

Smiles

CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2CCOC2)S(=O)(=O)c3ccc(N)cc3