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Substance Name: Talastine hydrochloride
RN: 16188-76-4
UNII: SBH6TU2VU4
InChIKey: PZSBWKCWXLBRCY-UHFFFAOYSA-N

Classification Codes

  • Antihistaminic
  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H21-N3-O.Cl-H

Molecular Weight

  • 343.8558
 
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Names and Synonyms

Name of Substance

  • Talastine hydrochloride

Synonyms

  • 4-Benzyl-2-(2-(dimethylamino)ethyl)-1(2H)-phthalazinone hydrochloride
  • Ahanon
  • HL 2186
  • Talastine HCl
  • Talastine hydrochloride
  • UNII-SBH6TU2VU4

Systematic Names

  • 1(2H)-Phthalazinone, 2-(2-(dimethylamino)ethyl)-4-(phenylmethyl)-, monohydrochloride (9CI)
  • 1(2H)-Phthalazinone, 4-benzyl-2-(2-(dimethylamino)ethyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 16188-76-4

FDA UNII

  • SBH6TU2VU4

Related Registry Number

  • 16188-61-7 (Parent)

System Generated Number

  • 0016188764

Molecular Formulas

Molecular Formula

  • C19-H21-N3-O.Cl-H

Molecular Formula Fragments

  • C19-H21-N3-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H21N3O.ClH/c1-21(2)12-13-22-19(23)17-11-7-6-10-16(17)18(20-22)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H

InChIKey

PZSBWKCWXLBRCY-UHFFFAOYSA-N

Smiles

CN(C)CCn1c(=O)c2ccccc2c(n1)Cc3ccccc3.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 116mg/kg (116mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 678, 1957.