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Substance Name: Esomeprazole magnesium [USAN:INN]
RN: 161973-10-0
UNII: 925R0D7W1O
InChIKey: KWORUUGOSLYAGD-YPPDDXJESA-N

Note

  • A highly effective inhibitor of gastric acid secretion used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits the H( )-K( )-ATPase ( H( )-K( )-EXCHANGING ATPASE) in the proton pump of GASTRIC PARIETAL CELLS.

Molecular Formula

  • C34-H36-Mg-N6-O6-S2

Molecular Weight

  • 713.1314
 

Names and Synonyms

Name of Substance

  • Esomeprazole magnesium [USAN:INN]

Synonyms

  • (-)-Omeprazole magnesium
  • (S)-Omeprazole magnesium
  • Esomeprazole magnesium
  • H 199/18
  • Nexium
  • Nexium 24hr
  • Nexium IV
  • Perprazole
  • UNII-925R0D7W1O

Systematic Names

  • Magnesium, bis(5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazolato)-, (T-4-(S),(S))-
  • Magnesium, bis(5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl-kappaO)-1H-benzimidazolato-kappaN1)-, (T-4)-

Registry Numbers

CAS Registry Number

  • 161973-10-0

FDA UNII

  • 925R0D7W1O

Other Registry Numbers

  • 202742-32-3
  • 302841-07-2
  • 320416-93-1
  • 371759-50-1
  • 372519-57-8
  • 376628-34-1

System Generated Number

  • 0161973100

Structure Descriptors

InChI

1S/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1

InChIKey

KWORUUGOSLYAGD-YPPDDXJESA-N

Smiles

[Mg+2].COc1ccc2[n-]c(nc2c1)[S@@](=O)Cc3ncc(C)c(OC)c3C.COc4ccc5[n-]c(nc5c4)[S@@](=O)Cc6ncc(C)c(OC)c6C