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Substance Name: Pazufloxacin methanesulfonate
RN: 163680-77-1
UNII: 2XI226J1HS
InChIKey: UDHGFPATQWQARM-FJXQXJEOSA-N

Molecular Formula

  • C16-H15-F-N2-O4.C-H4-O3-S

Molecular Weight

  • 414.4081
 
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Names and Synonyms

Results Name

  • Pazufloxacin methanesulfonate

Name of Substance

  • Pazufloxacin mesilate

Synonyms

  • Pasil
  • Pazucross
  • Pazufloxacin mesilate
  • Pazufloxacin mesylate
  • T 3762
  • UNII-2XI226J1HS

Systematic Name

  • 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)-, monomethanesulfonate

Registry Numbers

CAS Registry Number

  • 163680-77-1

FDA UNII

  • 2XI226J1HS

System Generated Number

  • 0163680771

Molecular Formulas

Molecular Formula

  • C16-H15-F-N2-O4.C-H4-O3-S

Molecular Formula Fragments

  • C-H4-O3-S
  • C16-H15-F-N2-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C16H15FN2O4.CH4O3S/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22;1-5(2,3)4/h4-5,7H,2-3,6,18H2,1H3,(H,21,22);1H3,(H,2,3,4)/t7-;/m0./s1

InChIKey

UDHGFPATQWQARM-FJXQXJEOSA-N

Smiles

C[C@H]1COc2c(c(cc3c2n1cc(c3=O)C(=O)O)F)C4(CC4)N.CS(=O)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 521mg/kg (521mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.
monkey LDLo intravenous 520mg/kg (520mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.
rat LDLo intravenous 391mg/kg (391mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.