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Substance Name: NK 1145
RN: 16487-37-9
InChIKey: QCNBFZDTSBLLIW-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H19-N-O.Cl-H

Molecular Weight

  • 253.771
 
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Names and Synonyms

Results Name

  • NK 1145

Synonyms

  • NK 1145
  • NK-1145 hydrochloride
  • Phenyl tropan-3alpha-yl ester
  • Tropine-3-beta-phenyl ether hydrochloride

Systematic Names

  • 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, phenyl ether, hydrochloride
  • 1-alpha-H,5-alpha-H-Tropane, 3-alpha-phenoxy- (8CI)
  • 8-Azabicyclo(3.2.1)octane, 8-methyl-3-phenoxy-, endo- (9CI)

Registry Numbers

CAS Registry Number

  • 16487-37-9

System Generated Number

  • 0016487379

Molecular Formulas

Molecular Formula

  • C14-H19-N-O.Cl-H

Molecular Formula Fragments

  • C14-H19-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C14H19NO.ClH/c1-15-11-7-8-12(15)10-14(9-11)16-13-5-3-2-4-6-13;/h2-6,11-12,14H,7-10H2,1H3;1H

InChIKey

QCNBFZDTSBLLIW-UHFFFAOYSA-N

Smiles

c1ccccc1OC1C[C@@H]2CC[C@@H](C1)N2C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 17500ug/kg (17.5mg/kg) BEHAVIORAL: EXCITEMENT

AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 517, 1968.
mouse LD50 oral 78mg/kg (78mg/kg) BEHAVIORAL: EXCITEMENT

AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 517, 1968.
mouse LD50 subcutaneous 17mg/kg (17mg/kg) BEHAVIORAL: EXCITEMENT

AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 517, 1968.
rat LDLo subcutaneous 45mg/kg (45mg/kg) BEHAVIORAL: EXCITEMENT

AUTONOMIC NERVOUS SYSTEM: PARASYMPATHOLYTIC
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 517, 1968.