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Substance Name: p58 Natural killer cell receptor
RN: 167975-17-9


  • A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
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Names and Synonyms

Name of Substance

  • p58 Natural killer cell receptor

MeSH Heading

  • Receptors, KIR


  • p58 NK Cell receptor
  • p58 NK Cell receptors
  • Receptor, p58 NK cell

Systematic Name

  • Receptor p58 (human clone cl-43 precursor)

Registry Numbers

CAS Registry Number

  • 167975-17-9

System Generated Number

  • 0167975179