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Substance Name: Lotrafiban [INN]
RN: 171049-14-2
UNII: KLQ306I83X
InChIKey: PYZOVVQJTLOHDG-FQEVSTJZSA-N

Note

  • A selective, nonpeptide antagonist of the human platelet fibrinogen receptor (glycoprotein IIb/IIIa) for treatment of coronary or cerebral atherosclerotic disease.

Molecular Formula

  • C23-H32-N4-O4

Molecular Weight

  • 428.5298
 
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Names and Synonyms

Name of Substance

  • Lotrafiban
  • Lotrafiban [INN]

Synonyms

  • (2S)-7-((4,4'-Bipiperidin)-1-ylcarbonyl)-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetic acid
  • Lotrafiban
  • SB 214857
  • UNII-KLQ306I83X

Systematic Name

  • 1H-1,4-Benzodiazepine-2-acetic acid, 7-((4,4'-bipiperidin)-1-ylcarbonyl)-2,3,4,5-tetrahydro-4-methyl-3-oxo-, (2S)-

Registry Numbers

CAS Registry Number

  • 171049-14-2

FDA UNII

  • KLQ306I83X

System Generated Number

  • 0171049142

Structure Descriptors

InChI

1S/C23H32N4O4/c1-26-14-18-12-17(2-3-19(18)25-20(23(26)31)13-21(28)29)22(30)27-10-6-16(7-11-27)15-4-8-24-9-5-15/h2-3,12,15-16,20,24-25H,4-11,13-14H2,1H3,(H,28,29)/t20-/m0/s1

InChIKey

PYZOVVQJTLOHDG-FQEVSTJZSA-N

Smiles

CN1Cc2cc(ccc2N[C@H](C1=O)CC(=O)O)C(=O)N3CCC(CC3)C4CCNCC4