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Substance Name: Exatecan [INN]
RN: 171335-80-1
UNII: OC71PP0F89
InChIKey: ZVYVPGLRVWUPMP-FYSMJZIKSA-N

Note

  • DX-8951a is hydrochloride & DX-895If is methanesulfonate; exatecan mesylate is a synonym for DX-8951f.

Molecular Formula

  • C24-H22-F-N3-O4

Molecular Weight

  • 435.4528
 

Classification Codes

  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Enzyme Inhibitors
  • Topoisomerase I Inhibitors
  • Topoisomerase Inhibitors
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Names and Synonyms

Name of Substance

  • DX 8951
  • Exatecan [INN]

Synonyms

  • (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione
  • DX 8951
  • Exatecan
  • UNII-OC71PP0F89

Systematic Names

  • 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S,9S)-
  • 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-

Registry Numbers

CAS Registry Number

  • 171335-80-1

FDA UNII

  • OC71PP0F89

System Generated Number

  • 0171335801

Structure Descriptors

InChI

1S/C24H22FN3O4/c1-3-24(31)14-6-18-21-12(8-28(18)22(29)13(14)9-32-23(24)30)19-16(26)5-4-11-10(2)15(25)7-17(27-21)20(11)19/h6-7,16,31H,3-5,8-9,26H2,1-2H3/t16-,24-/m0/s1

InChIKey

ZVYVPGLRVWUPMP-FYSMJZIKSA-N

Smiles

CC[C@@]1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5cc(c(c6c5c4[C@H](CC6)N)C)F)O