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Substance Name: Prednisolone sodium succinate [USP:JAN]
RN: 1715-33-9
UNII: 8223RR9DWF
InChIKey: FKKAEMQFOIDZNY-CODXZCKSSA-M

Classification Codes

  • Drug / Therapeutic Agent
  • Glucocorticoid
  • Hormone
  • Reproductive Effect

Molecular Formulas

  • C25-H31-Na-O8
  • C25-H31-O8.Na
  • C25-H32-O8.Na

Molecular Weight

  • 482.5019
 
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Names and Synonyms

Name of Substance

  • Prednisolone 21-succinate sodium salt
  • Prednisolone sodium succinate [USP:JAN]

Synonyms

  • 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(sodium succinate)
  • Di-Adreson F-aquosum
  • EINECS 216-995-1
  • Methyprednisolone sodium succinate
  • Meticortelane
  • Meticortelone, soluble
  • NSC 9151
  • Prednisolone 21-hemisuccinate sodium
  • Prednisolone 21-hemisuccinate sodium salt
  • Prednisolone 21-sodium succinate
  • Prednisolone 21-succinate sodium
  • Prednisolone 21-succinate sodium salt
  • Prednisolone sodium 21-hemisuccinate
  • Prednisolone sodium hemisuccinate
  • Prednisolone sodium succinate
  • Prednisolone sodium succinate, injection
  • Predonine soluble
  • Sodium prednisolone 21-hemisuccinate
  • Solu-Decortin
  • Solu-delta-Cortef (Veterinary)
  • UNII-8223RR9DWF

Systematic Names

  • Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(hydrogen succinate), monosodium salt
  • Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-(hydrogen succinate), monosodium salt (8CI)
  • Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, monosodium salt, (11beta)-
  • Pregna-1,4-diene-3,20-dione, 21-(3-carboxyl-1-oxopropoxy)-11,17-dihydroxy-, monosodium salt, (11beta)-

Registry Numbers

CAS Registry Number

  • 1715-33-9

FDA UNII

  • 8223RR9DWF

System Generated Number

  • 0001715339

Molecular Formulas

Molecular Formulas

  • C25-H31-Na-O8
  • C25-H31-O8.Na
  • C25-H32-O8.Na

Molecular Formula Fragments

  • C25-H31-O8
  • C25-H32-O8
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C25H32O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChIKey

FKKAEMQFOIDZNY-CODXZCKSSA-M

Smiles

[C@@]12([C@H]([C@H]3[C@H]([C@H](C2)O)[C@@]2(C(=CC(=O)C=C2)CC3)C)CC[C@@]1(C(=O)COC(=O)CCC(=O)[O-])O)C.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 1125mg/kg (1125mg/kg)   Pharmaceutical Chemistry Journal Vol. 16, Pg. 63, 1982.
rat LD50 intravenous 770mg/kg (770mg/kg)   Pharmaceutical Chemistry Journal Vol. 16, Pg. 63, 1982.