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Substance Name: Serotonin 1Dbeta receptor
RN: 172727-63-8


  • A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
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Names and Synonyms

Name of Substance

  • Serotonin 1Dbeta receptor

MeSH Heading

  • Receptor, Serotonin, 5-HT1B


  • 5-HT(1Dbeta) Receptor
  • Receptor, serotonin type 1Dbeta
  • Serotonin 1Dbeta receptor gene product
  • Serotonin 1Dbeta receptors

Systematic Name

  • Receptor, serotoninergic (rabbit subtype 1Dbeta reduced)

Registry Numbers

CAS Registry Number

  • 172727-63-8

System Generated Number

  • 0172727638