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Substance Name: Ambrisentan [INN:BAN:JAN]
RN: 177036-94-1
UNII: HW6NV07QEC
InChIKey: OUJTZYPIHDYQMC-LJQANCHMSA-N

Note

  • An ET(A) receptor antagonist and antihypertensive agent; studied for use as in pulmonary arterial hypertension.

Molecular Formula

  • C22-H22-N2-O4

Molecular Weight

  • 378.4258
 

Classification Codes

  • Antihypertensive Agents
  • Cardiovascular Agents

Names and Synonyms

Name of Substance

  • Ambrisentan
  • Ambrisentan [INN:BAN:JAN]

Synonyms

  • (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
  • Ambrisentan
  • BSF 208075
  • BSF-208075
  • Letairis
  • LU 208075
  • LU-208075
  • LU208075
  • UNII-HW6NV07QEC
  • Volibris

Registry Numbers

CAS Registry Number

  • 177036-94-1

FDA UNII

  • HW6NV07QEC

System Generated Number

  • 0177036941

Structure Descriptors

InChI

1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1

InChIKey

OUJTZYPIHDYQMC-LJQANCHMSA-N

Smiles

COC([C@H](Oc1nc(C)cc(C)n1)C(=O)O)(c2ccccc2)c3ccccc3