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Substance Name: Choriogonadotropin Alfa [USAN:INN:BAN]
RN: 177073-44-8

Note

  • Ovidrel(TM) PreFilled Syringe (choriogonadotropin alfa injection) is a sterile liquid preparation of choriogonadotropin alfa (recombinant human Chorionic Gonadotropin, r-hCG). Choriogonadotropin alfa is a water soluble glycoprotein consisting of two non-covalently linked subunits - designated slpha and beta - consisting of 92 and 145 amino acid residues, respectively, with carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha - chain of r-hCG is identical to that of the alpha - chain of hCG, FSH and LH. The glycoform pattern of the alpha - subunit of r-hCG is closely comparable to urinary derived hCG (u-hCG), the differences mainly being due to the branching and sialylation extent of the oligosaccharides. The beta - chain has both O- and N-glycosylation sites and its structure and glycosylation pattern are also very similar to that of u-hCG.

Molecular Formula

  • Unspecified

Molecular Weight

  • 25737.7588
 

Classification Codes

  • Cryptorchidism Therapy Adjuvant (Recombinant Human Chorionic Gonadotropin (rhCG))
  • Treatment of Infertility
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Links to Resources

Names and Synonyms

Name of Substance

  • Choriogonadotropin Alfa [USAN:INN:BAN]

MeSH Heading

  • Chorionic gonadotropin

Synonyms

  • ATC Code G03 GA Gonadotropins
  • Choriogonadotropin alfa
  • Gonadotropin, chorionic (human alpha-subunit protein moiety reduced), complex with chorionic gonadotropin (human beta-subunit protein moiety reduced)
  • Human chorionic gonadotropin (alpha-subunit protein moiety reduced), complex with human chorionic gonadotropin (beta-subunit protein moiety reduced). Molecular weight is 38,000 daltons
  • Human chorionic gonadotropin, glycoform alpha
  • Ovidrel
  • Ovitrelle
  • Pregnyl
  • UNII-20ED16GHEB
  • UNII-6413W06WR3

Systematic Name

  • Gonadotropin, chorionic (human alpha-subunit protein moiety reduced), complex with chorionic gonadotropin (human beta-subunit protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 177073-44-8

FDA UNIIs

  • 20ED16GHEB
  • 6413W06WR3

System Generated Number

  • 0177073448

Structure Descriptors

Smiles

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