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Substance Name: Basiliximab [USAN:INN:BAN]
RN: 179045-86-4
UNII: 9927MT646M

Note

  • A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Antiviral (COVID-19)
  • Immunologic Factors
  • Immunosuppressant (Monoclonal Antibody)
  • Immunosuppressive Agents

Names and Synonyms

Name of Substance

  • Basiliximab [USAN:INN:BAN]

MeSH Heading

  • Basiliximab

Synonyms

  • Basiliximab
  • HSDB 8175
  • Immunoglobulin G 1 (human-mouse monoclonal CHI621 heavy chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal CHI621 light chain, dimer
  • Immunoglobulin G1 (human-mouse monoclonal CHI621 heavy chain antihuman interleukin 2 receptor), disulfide with human-mouse monoclonal CHI621 light chain, dimer
  • Immunoglobulin G1, anti-(human interleukin 2 receptor) (human-mouse monoclonal CHI621 gamma1-chain), disulfide with human-mouse monoclonal CHI621 light chain, dimer
  • SDZ-CHI-621
  • Simulect
  • UNII-9927MT646M

Systematic Name

  • Immunoglobulin G1, anti-(human interleukin 2 receptor)(human-mouse monoclonal CHI621 gamma1-chain), disulfide with human-mouse monoclonal CHI621 light chain, dimer

Registry Numbers

CAS Registry Number

  • 179045-86-4

FDA UNII

  • 9927MT646M

System Generated Number

  • 0179045864