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Substance Name: Ravulizumab [USAN]
RN: 1803171-55-2

Molecular Formula

  • C6430-H9888-N1696-O2028-S48 (unglycosylated)

Classification Code

  • Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH), Atypical Hemolytic Uremic Syndrome (AHUS)
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Links to Resources

NLM Resources (File Locators)

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Names and Synonyms

Name of Substance

  • Ravulizumab [USAN]


  • ALXN1210
  • Immunoglobulin G2/G4-kappa, anti-(human complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4)); humanized mouse monoclonal antibody: gamma2/gamma4 heavy chain (1-447) (human VH (Homo sapiens IGHV1-46*01 (82%)-(IGHD)-IGHJ4*01 (93%)) (8.8.15) (1-122) -Homo sapiens IGHG2*01(CH1-H) (123-232) -Homo sapiens IGHG4*01(CH2 E3>P(235), L5>V(237), G6>A(238); CH3 M88>L(429), N94>S(435), K107>del(448)) (233-447)), (136-214')-disulfide with kappa light chain (1'-214') (human V-KAPPA (Homo sapiens IGKV1-39*01 (84%)-IGKJ1*01) (6.3.9) (1'-107') -Homo sapiens IGKC*01 (108'-214')); dimer (224-224'':225-225'':228-228'':231-231'')-tetrakisdisulfide
  • Ravulizumab
  • UNII-C3VX249T6L

Systematic Name

  • Immunoglobulin G2/G4, anti-(human complement C5) (human-Mus musculus ALXN1210 heavy chain), disulfide with human-Mus musculus ALXN1210 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 1803171-55-2


  • C3VX249T6L

System Generated Number

  • 1803171552