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Substance Name: Caspase-2
RN: 182372-14-1


  • A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
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Names and Synonyms

MeSH Heading

  • Caspase 2


  • Caspase 2
  • Caspase-2

Registry Numbers

CAS Registry Number

  • 182372-14-1

System Generated Number

  • 0182372141