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Substance Name: Risdiplam [USAN:INN]
RN: 1825352-65-5
UNII: 76RS4S2ET1
InChIKey: ASKZRYGFUPSJPN-UHFFFAOYSA-N

Note

  • Small-molecule SMN2 pre-mRNA splicing modifier.

Molecular Formula

  • C22-H23-N7-O

Molecular Weight

  • 401.4717
 

Classification Codes

  • Neuromuscular Agents
  • Peripheral Nervous System Agents
  • Treatment of Spinal Muscular Atrophy (SMA)
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Names and Synonyms

Results Name

  • Risdiplam [USAN:INN]

Name of Substance

  • Risdiplam
  • Risdiplam [USAN]

Synonyms

  • 4H-Pyrido(1,2-a)pyrimidin-4-one, 7-(4,7-diazaspiro(2.5)oct-7-yl)-2-(2,8-dimethylimidazo(1,2-b)pyridazin-6-yl)-
  • 7-(4,7-Diazaspiro(2.5)oct-7-yl)-2-(2,8-dimethylimidazo(1,2-b)pyridazin-6-yl)-4H-pyrido(1,2-a)pyrimidin-4-one
  • RG-7916
  • RG7916
  • Risdiplam
  • Risdiplam [INN]
  • RO7034067
  • UNII-76RS4S2ET1
  • WHO 10614

Registry Numbers

CAS Registry Number

  • 1825352-65-5

FDA UNII

  • 76RS4S2ET1

System Generated Number

  • 1825352655

Structure Descriptors

InChI

InChI=1S/C22H23N7O/c1-14-9-18(26-29-11-15(2)24-21(14)29)17-10-20(30)28-12-16(3-4-19(28)25-17)27-8-7-23-22(13-27)5-6-22/h3-4,9-12,23H,5-8,13H2,1-2H3

InChIKey

ASKZRYGFUPSJPN-UHFFFAOYSA-N

Smiles

Cc1cn2nc(cc(C)c2n1)C3=CC(=O)N4C=C(C=CC4=N3)N5CCNC6(CC6)C5