Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Erlotinib hydrochloride [USAN:INN]
RN: 183319-69-9
UNII: DA87705X9K
InChIKey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N

Note

  • A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.

Molecular Formula

  • C22-H23-N3-O4.Cl-H

Molecular Weight

  • 429.9016
 

Classification Codes

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors

Names and Synonyms

Name of Substance

  • Erlotinib hydrochloride [USAN:INN]

MeSH Heading

  • Erlotinib Hydrochloride

Synonyms

  • 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride
  • CP 358774
  • CP-358,774-01
  • Erlotinib HCl
  • Erlotinib hydrochloride
  • OSI 774
  • OSI-774
  • Tarceva
  • UNII-DA87705X9K

Systematic Name

  • 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 183319-69-9

FDA UNII

  • DA87705X9K

System Generated Number

  • 0183319699

Molecular Formulas

Molecular Formula

  • C22-H23-N3-O4.Cl-H

Molecular Formula Fragments

  • C22-H23-N3-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H

InChIKey

GTTBEUCJPZQMDZ-UHFFFAOYSA-N

Smiles

n1cnc(c2cc(c(cc12)OCCOC)OCCOC)Nc1cc(ccc1)C#C.Cl