Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Sangivamycin
RN: 18417-89-5
InChIKey: OBZJZDHRXBKKTJ-JTFADIMSSA-N

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibiotics, Antineoplastic
  • Antineoplastic Agents
  • Drug / Therapeutic Agent
  • Mutation Data
  • Natural Product

Molecular Formula

  • C12-H15-N5-O5

Molecular Weight

  • 309.2805
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Sangivamycin

Synonyms

  • 4-Amino-7-beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carboxamide
  • 7-Deazaadenosine-7-carboxamide
  • Antibiotic B 14437 (base)
  • Antibiotic B-14437
  • B 90912
  • B-14437
  • BRN 0626355
  • NSC-65346
  • Sangivamycin
  • SKI 27013

Systematic Name

  • 7H-Pyrrolo(2,3-d)pyrimidine-5-carboxamide, 4-amino-7-beta-D-ribofuranosyl-

Registry Numbers

CAS Registry Number

  • 18417-89-5

System Generated Number

  • 0018417895

Structure Descriptors

InChI

1S/C12H15N5O5/c13-9-6-4(10(14)21)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)22-12/h1,3,5,7-8,12,18-20H,2H2,(H2,14,21)(H2,13,15,16)/t5-,7-,8-,12-/m1/s1

InChIKey

OBZJZDHRXBKKTJ-JTFADIMSSA-N

Smiles

c1c(c2c(ncnc2n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N)C(=O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 5mg/kg (5mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 5, Pg. 313, 1981.
mouse LD50 oral 11mg/kg (11mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LDLo intraperitoneal 4mg/kg (4mg/kg)   National Cancer Institute Report. Vol. -, Pg. 269, 1967.
rat LDLo intraperitoneal 1200ug/kg (1.2mg/kg)   National Cancer Institute Report. Vol. -, Pg. 269, 1967.