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Substance Name: Etanercept [USAN:INN:BAN]
RN: 185243-69-0
UNII: OP401G7OJC

Note

  • A recombinant version of soluble human TNF receptor that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.

Molecular Formulas

  • C2224-H3472-N618-O701-S36
  • Unspecified

Molecular Weight

  • 51166.8153
 

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Gastrointestinal Agents
  • Immunologic Factors
  • Immunosuppressive Agents
  • Peripheral Nervous System Agents
  • Sensory System Agents
  • To Decrease Signs and Symptoms of Rheumatoid Arthritis

Names and Synonyms

Name of Substance

  • Etanercept [USAN:INN:BAN]
  • Etanercept-szzs
  • TNFR-Fc fusion protein

MeSH Heading

  • Etanercept

Synonyms

  • 1-235-Tumor necrosis factor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human gamma1-chain Fc fragment), dimer
  • Enbrel
  • Erelzi
  • Etanercept
  • Etanercept-szzs [Biosimilar]
  • HSDB 7849
  • Recombinant human dimeric TNF receptor type II-IgG fusion protein
  • Recombinant human TNF
  • rhu TNFR:Fc
  • TNF receptor type II-IgG fusion protein
  • TNFR-Fc
  • TNFR:Fc
  • TNR 001
  • UNII-OP401G7OJC

Systematic Name

  • 1-235-Tumor necrosis factor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human gamma1-chain Fc fragment)

Registry Numbers

CAS Registry Number

  • 185243-69-0

FDA UNII

  • OP401G7OJC

Other Registry Number

  • 200013-86-1

System Generated Number

  • 0185243690