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Substance Name: GYKI-16084
RN: 185739-21-3
UNII: N714HRW3DJ
InChIKey: FJNRJBQUOQLUNQ-CYBMUJFWSA-N

Note

  • The combined alpha1- and postsynaptically selective alpha2-blocker GYKI-16084 significantly improved the AUA symptom scores and increased Q(max) in patients with BPH, without inducing any adverse reaction, orthostatic changes or erectile dysfunction.

Molecular Formula

  • C16-H19-N3-O3

Molecular Weight

  • 301.344
 
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Names and Synonyms

Name of Substance

  • GYKI-16084

Synonyms

  • GYKI 16084
  • UNII-N714HRW3DJ

Systematic Name

  • 3(2H)-Pyridazinone, 2-(3-((((2R)-2,3-dihydro-1,4-benzodioxin-2-yl)methyl)amino)propyl)-

Registry Numbers

CAS Registry Number

  • 185739-21-3

FDA UNII

  • N714HRW3DJ

Other Registry Number

  • 625853-96-5

System Generated Number

  • 0185739213

Structure Descriptors

InChI

1S/C16H19N3O3/c20-16-7-3-9-18-19(16)10-4-8-17-11-13-12-21-14-5-1-2-6-15(14)22-13/h1-3,5-7,9,13,17H,4,8,10-12H2/t13-/m1/s1

InChIKey

FJNRJBQUOQLUNQ-CYBMUJFWSA-N

Smiles

c1(cccnn1CCCNC[C@H]1Oc2c(OC1)cccc2)=O