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Substance Name: Tofimilast [USAN:INN]
RN: 185954-27-2
UNII: 5D7022962A
InChIKey: DHCOPPHTVOXDKU-UHFFFAOYSA-N

Note

  • Inhibits eosinophil phosphodiesterase.

Molecular Formula

  • C18-H21-N5-S

Molecular Weight

  • 339.4649
 

Classification Codes

  • PDE4 Inhibitor
  • Phosphodiesterase Isoenzyme 4 Inhibitor
  • Treatment Chronic Obstructive Disease
  • Treatment of Asthma
  • Treatment of Asthma and Chronic Obstructive Disease (Phosphodiesterase Isoenzyme 4) (PDE4 Inhibitor)
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Names and Synonyms

Name of Substance

  • Tofimilast
  • Tofimilast [USAN:INN]

Synonyms

  • 5H-Pyrazolo(3,4-c)-1,2,4-triazolo(4,3-a)pyridine, 9-cyclopentyl-7-ethyl-6,9-dihydro-3-(2-thienyl)-
  • CP-325,366
  • Tofimilast
  • UNII-5D7022962A

Systematic Name

  • 9-Cyclopentyl-7-ethyl-3-(thiophen-2-yl)-6,9-dihydro-5H-pyrazolo(3,4-c)-1,2,4-triazolo(4,3-a)pyridine

Registry Numbers

CAS Registry Number

  • 185954-27-2

FDA UNII

  • 5D7022962A

System Generated Number

  • 0185954272

Structure Descriptors

InChI

1S/C18H21N5S/c1-2-14-13-9-10-22-17(15-8-5-11-24-15)19-20-18(22)16(13)23(21-14)12-6-3-4-7-12/h5,8,11-12H,2-4,6-7,9-10H2,1H3

InChIKey

DHCOPPHTVOXDKU-UHFFFAOYSA-N