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Substance Name: Edodekin alfa [USAN:INN]
RN: 187348-17-0
UNII: 31Z82G8ME1

Note

  • A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Adjuvants, Immunologic
  • Angiogenesis Inhibitors
  • Angiogenesis Modulating Agents
  • Antiasthmatic
  • Antineoplastic Agents
  • Growth Inhibitors
  • Growth Substances
  • Immunologic Factors
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Names and Synonyms

Name of Substance

  • Edodekin alfa [USAN:INN]
  • Interleukin-12

MeSH Heading

  • Interleukin-12

Synonyms

  • Edodekin alfa
  • Interleukin 12 (human). Molecular weight for glycosylated protein is 70,000-75,000 daltons
  • Recombinant Human Interleukin-12
  • rHuIL-12
  • Ro 24-7472
  • Ro 24-7472/000
  • UNII-31Z82G8ME1

Systematic Name

  • Interleukin 12 (human)

Registry Numbers

CAS Registry Number

  • 187348-17-0

FDA UNII

  • 31Z82G8ME1

System Generated Number

  • 0187348170