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Substance Name: Darovasertib [USAN]
RN: 1874276-76-2
UNII: E0YF0M8O09
InChIKey: XXJXHXJWQSCNPX-UHFFFAOYSA-N

Classification Code

  • Treatment of Metastatic Uveal Melanoma and other Tumors Harboring Mutations in GNAQ orGNA11 that Activate the PKC Signaling Pathway

Molecular Formula

  • C22-H23-F3-N8-O

Molecular Weight

  • 472.4662
 
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Names and Synonyms

Name of Substance

  • Darovasertib [USAN]
  • LXS-196

Synonyms

  • 2-Pyrazinecarboxamide, 3-amino-N-(3-(4-amino-4-methyl-1-piperidinyl)-2-pyridinyl)-6-(3-(trifluoromethyl)-2-pyridinyl)-
  • 3-Amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide
  • IDE-196
  • IDE196
  • LXS-196
  • LXS196
  • NVP-LXS-196
  • UNII-E0YF0M8O09
  • WHO 11416

Registry Numbers

CAS Registry Number

  • 1874276-76-2

FDA UNII

  • E0YF0M8O09

System Generated Number

  • 1874276762

Structure Descriptors

InChI

1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)

InChIKey

XXJXHXJWQSCNPX-UHFFFAOYSA-N

Smiles

CC1(N)CCN(CC1)c2cccnc2NC(=O)c3nc(cnc3N)c4ncccc4C(F)(F)F