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Substance Name: Eptifibatide [INN:BAN]
RN: 188627-80-7
UNII: NA8320J834
InChIKey: CZKPOZZJODAYPZ-LROMGURASA-N
Notes
- Cyclic peptide that acts as a platelet glycoprotein IIB-IIIA antagonist, reversibly inhibiting the binding of FIBRINOGEN; VON WILLEBRAND FACTOR; and other adhesive molecules to the GPIIB-IIIA RECEPTORS of platelets. It is used in the management of UNSTABLE ANGINA and in patients undergoing coronary ANGIOPLASTY and stenting procedures.
- Used in clinical studies as a platelet glycoprotein IIB/IIIA antagonist.
Molecular Formula
- C35-H49-N11-O9-S2
Molecular Weight
- 831.9721
Classification Codes
- Hematologic Agents
- Platelet Aggregation Inhibitors
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Names and Synonyms
Name of Substance
- Eptifibatide
- Eptifibatide [INN:BAN]
MeSH Heading
- Eptifibatide
Synonyms
- Eptifibatide
- HSDB 8313
- Integrelin
- Integrilin
- N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide
- UNII-NA8320J834
Systematic Name
- L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic (1-6)-disulfide
Registry Numbers
CAS Registry Number
- 188627-80-7
FDA UNII
- NA8320J834
Other Registry Numbers
- 148031-34-9
- 157630-07-4
System Generated Number
- 0188627807