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Substance Name: Actinomycin X2
RN: 18865-48-0
InChIKey: GQZJMUMSSGCVFS-UHFFFAOYSA-N
Classification Codes
- Drug / Therapeutic Agent
- Mutation Data
- Natural Product
Molecular Formula
- C62-H84-N12-O17
Molecular Weight
- 1269.41
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Names and Synonyms
Synonyms
- 1H-Pyrrolo(2,1-i)(1,4,7,10,13)oxatetraazacyclohexadecine, cyclic peptide deriv.
- 3H-Phenoxazine, actinomycin D deriv.
- Actinomycin D, 3A-(4-oxo-L-proline)-
- Actinomycin-V
- EINECS 242-636-3
Systematic Names
- Actinomycin D, 3A-(4-oxo-L-proline)-
- Actinomycin X2
Registry Numbers
CAS Registry Number
- 18865-48-0
Other Registry Numbers
- 1402-61-5
- 23714-40-1
System Generated Number
- 0018865480
Structure Descriptors
InChI
1S/C62H84N12O17/c1-26(2)42-59(85)73-21-17-18-36(73)57(83)69(13)24-38(76)71(15)48(28(5)6)61(87)89-32(11)44(55(81)65-42)67-53(79)35-20-19-30(9)51-46(35)64-47-40(41(63)50(78)31(10)52(47)91-51)54(80)68-45-33(12)90-62(88)49(29(7)8)72(16)39(77)25-70(14)58(84)37-22-34(75)23-74(37)60(86)43(27(3)4)66-56(45)82/h19-20,26-29,32-33,36-37,42-45,48-49H,17-18,21-25,63H2,1-16H3,(H,65,81)(H,66,82)(H,67,79)(H,68,80)InChIKey
GQZJMUMSSGCVFS-UHFFFAOYSA-NSmiles
c1(ccc(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 300ug/kg (0.3mg/kg) | Journal of Antibiotics. Vol. 38, Pg. 1625, 1985. | |
mouse | LD50 | intravenous | 1mg/kg (1mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(2), Pg. 48, 1980. | |
mouse | LD50 | subcutaneous | 300ug/kg (0.3mg/kg) | "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977Vol. -, Pg. 427, 1977. |