Substance Name: Natalizumab [USAN:INN:BAN]
RN: 189261-10-7
UNII: 3JB47N2Q2P
Note
- A humanized monoclonal immunoglobulin G4 antibody to human INTEGRIN ALPHA4 that binds to the alpha4 subunit of INTEGRIN ALPHA4BETA1 and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS and CROHN'S DISEASE.
Molecular Formula
- Unspecified
Classification Code
- Immunologic Factors
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Natalizumab
- Natalizumab [USAN:INN:BAN]
MeSH Heading
- Natalizumab
Synonyms
- Antegren
- HSDB 8174
- Immunoglobulin G 4 (human-mouse monoclonal AN100226 4-chain anti-human integrin 4), disulfide with human-mouse monoclonal AN100226 light chain, dimer
- Natalizumab
- Tysabri
- UNII-3JB47N2Q2P
Systematic Name
- Immunoglobulin G4, anti-(human integrin alpha4) (human-mouse monoclonal AN100226 gamma4-chain), disulfide with human-mouse monoclonal AN100226 light chain, dimer
Registry Numbers
CAS Registry Number
- 189261-10-7
FDA UNII
- 3JB47N2Q2P
System Generated Number
- 0189261107