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Substance Name: Natalizumab [USAN:INN:BAN]
RN: 189261-10-7
UNII: 3JB47N2Q2P

Note

  • A humanized monoclonal immunoglobulin G4 antibody to human INTEGRIN ALPHA4 that binds to the alpha4 subunit of INTEGRIN ALPHA4BETA1 and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS and CROHN'S DISEASE.

Molecular Formula

  • Unspecified
 

Classification Code

  • Immunologic Factors

Names and Synonyms

Name of Substance

  • Natalizumab
  • Natalizumab [USAN:INN:BAN]

MeSH Heading

  • Natalizumab

Synonyms

  • Antegren
  • HSDB 8174
  • Immunoglobulin G 4 (human-mouse monoclonal AN100226 4-chain anti-human integrin 4), disulfide with human-mouse monoclonal AN100226 light chain, dimer
  • Natalizumab
  • Tysabri
  • UNII-3JB47N2Q2P

Systematic Name

  • Immunoglobulin G4, anti-(human integrin alpha4) (human-mouse monoclonal AN100226 gamma4-chain), disulfide with human-mouse monoclonal AN100226 light chain, dimer

Registry Numbers

CAS Registry Number

  • 189261-10-7

FDA UNII

  • 3JB47N2Q2P

System Generated Number

  • 0189261107