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Substance Name: Lonetil M3
RN: 1897-96-7
InChIKey: JKWBQCHTVBSJDC-UHFFFAOYSA-N

Note

  • Russian Drug.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H16-N2-O2

Molecular Weight

  • 280.3254
 
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Names and Synonyms

Name of Substance

  • Lonetil M3

Synonyms

  • 2-Methyl-3-(4'-aethoxyphenyl)chinazolinone(4)
  • 2-Methyl-3-(4'-aethoxyphenyl)chinazolinone(4) [German]
  • 3-(p-Ethoxyphenyl)-2-methyl-4(3H)-quinazolinone
  • 4(3H)-Quinazolinone, 3-(4-ethoxyphenyl)-2-methyl-
  • 5-24-03-00146 (Beilstein Handbook Reference)
  • B 146
  • BRN 0255500
  • Lonethyl
  • Lonetil

Systematic Name

  • 4(3H)-Quinazolinone, 3-(p-ethoxyphenyl)-2-methyl-

Registry Numbers

CAS Registry Number

  • 1897-96-7

System Generated Number

  • 0001897967

Structure Descriptors

InChI

1S/C17H16N2O2/c1-3-21-14-10-8-13(9-11-14)19-12(2)18-16-7-5-4-6-15(16)17(19)20/h4-11H,3H2,1-2H3

InChIKey

JKWBQCHTVBSJDC-UHFFFAOYSA-N

Smiles

CCOc1ccc(cc1)n2c(nc3ccccc3c2=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1gm/kg (1000mg/kg)   Archives of Toxicology, Supplement. Vol. 1, Pg. 379, 1978.
mouse LD50 oral 3420mg/kg (3420mg/kg)   Archives of Toxicology, Supplement. Vol. 1, Pg. 379, 1978.
mouse LD50 parenteral 3gm/kg (3000mg/kg) BEHAVIORAL: ANALGESIA

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Pharmaceutical Chemistry Journal Vol. 7, Pg. 626, 1973.
rat LD50 intraperitoneal 1900mg/kg (1900mg/kg)   Archives of Toxicology, Supplement. Vol. 1, Pg. 379, 1978.
rat LD50 oral 4800mg/kg (4800mg/kg)   Archives of Toxicology, Supplement. Vol. 1, Pg. 379, 1978.