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Substance Name: Euprocin hydrochloride [USAN]
RN: 18984-80-0
UNII: EVA0339N2N
InChIKey: SIEYZYONZYIIJH-AGSMNRHJSA-N

Classification Codes

  • Anesthetic (Topical)
  • Drug / Therapeutic Agent

Molecular Formula

  • C24-H34-N2-O2.2Cl-H

Molecular Weight

  • 455.4664
 
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Names and Synonyms

Name of Substance

  • Euprocin hydrochloride [USAN]

Synonyms

  • 6-Quinolinol, 4-((1-methoxybutoxy)(5-vinyl-2-quinuclidinyl)methyl)-, dihydrochloride
  • Eucupin dihydrochloride
  • Euprocin HCl
  • Euprocin hydrochloride
  • Isoamyl hydrocupreine dihydrochloride
  • O(sup 6)'-Isopentylhydrocupreinedihydrochloride
  • UNII-EVA0339N2N
  • Wl 287

Systematic Names

  • Cinchonan-9-ol, 10,11-dihydro-6'-(3-methylbutoxy)-, dihydrochloride, (8alpha,9R)-
  • Hydrocupreine, O(Sup 6')-isopentyl-, dihydrochloride

Mixture Name

  • Otodyne

Registry Numbers

CAS Registry Number

  • 18984-80-0

FDA UNII

  • EVA0339N2N

System Generated Number

  • 0018984800

Molecular Formulas

Molecular Formula

  • C24-H34-N2-O2.2Cl-H

Molecular Formula Fragments

  • C24-H34-N2-O2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C24H34N2O2.2ClH/c1-4-17-15-26-11-8-18(17)13-23(26)24(27)20-7-10-25-22-6-5-19(14-21(20)22)28-12-9-16(2)3;;/h5-7,10,14,16-18,23-24,27H,4,8-9,11-13,15H2,1-3H3;2*1H/t17-,18-,23-,24+;;/m0../s1

InChIKey

SIEYZYONZYIIJH-AGSMNRHJSA-N

Smiles

CC[C@H]1C[N@@]2CC[C@H]1C[C@H]2[C@@H](c3ccnc4c3cc(cc4)OCCC(C)C)O.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 6820ug/kg (6.82mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BLOOD: OTHER CHANGES
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920.
cat LDLo subcutaneous 50mg/kg (50mg/kg) CARDIAC: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920.
mouse LDLo subcutaneous 300mg/kg (300mg/kg) CARDIAC: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 11, Pg. 257, 1920.
rat LD50 intravenous 20mg/kg (20mg/kg)   Compilation of LD50 Values of New Drugs.
rat LDLo subcutaneous 800mg/kg (800mg/kg)   Compilation of LD50 Values of New Drugs.