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Substance Name: Tenecteplase [USAN:INN:BAN]
RN: 191588-94-0


  • A triple combination mutant of alteplase developed to circumvent some of the limitations of fibrinolytic therapies.

Molecular Formula

  • Unspecified

Classification Codes

  • Cardiovascular Agents
  • Fibrin Modulating Agents
  • Fibrinolytic Agents
  • Hematologic Agents
  • Treatment of Acute Thrombotic Disorders
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Names and Synonyms

Name of Substance

  • Tenecteplase [USAN:INN:BAN]

MeSH Heading

  • Tenecteplase


  • 103-L-Asparagine-117-L-glutamine-296-L-alanine-297-L-alanine-298-L-alanine-299-L-alanineplasminogen activator (human tissue type). Molecular weight is approximately 58,742 daltons (polypeptide portion only)
  • Metalyse
  • Tenecteplase
  • TNK-tPA
  • TNKase
  • UNII-WGD229O42W

Systematic Name

  • Plasminogen activator (human tissue-type), 103-L-asparagine-117-L-glutamine-296-L-alanine-297-L-alanine-298-L-alanine-299-alanine-

Registry Numbers

CAS Registry Number

  • 191588-94-0


  • WGD229O42W

System Generated Number

  • 0191588940