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Substance Name: Trimeprazine hydrochloride
RN: 1936-51-2
UNII: 5MJ295MM20
InChIKey: QUVSTPKPFAPBQU-UHFFFAOYSA-N

Note

  • A phenothiazine derivative that is used as an antipruritic.

Classification Code

  • Antipruritics

Molecular Formula

  • C18-H22-N2-S.Cl-H

Molecular Weight

  • 334.9127
 
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Names and Synonyms

Results Name

  • Trimeprazine hydrochloride

Name of Substance

  • Trimeprazine hydrochloride

Synonyms

  • (Methyl-2-dimethylamino-3-propyl)-10-phenothiazine hydrochloride
  • (Methyl-2-dimethylamino-3-propyl)-10-phenothiazine hydrochloride [French]
  • 6549 RP
  • Alimemazin hydrochloride
  • Trimeprazine HCl
  • Trimeprazine hydrochloride
  • UNII-5MJ295MM20

Systematic Name

  • Phenothiazine, 10-(3-dimethylamino-2-methylpropyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 1936-51-2

FDA UNII

  • 5MJ295MM20

System Generated Number

  • 0001936512

Molecular Formulas

Molecular Formula

  • C18-H22-N2-S.Cl-H

Molecular Formula Fragments

  • C18-H22-N2-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C18H22N2S.ClH/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;/h4-11,14H,12-13H2,1-3H3;1H

InChIKey

QUVSTPKPFAPBQU-UHFFFAOYSA-N

Smiles

CC(CN1c2ccccc2Sc3c1cccc3)CN(C)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 55mg/kg (55mg/kg) AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" Archives Internationales de Pharmacodynamie et de Therapie. Vol. 151, Pg. 515, 1964.
mouse LD50 oral 300mg/kg (300mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 115, Pg. 90, 1958.
mouse LD50 subcutaneous 300mg/kg (300mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 115, Pg. 90, 1958.