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Substance Name: Galantamine hydrobromide [USAN:USP]
RN: 1953-04-4
UNII: MJ4PTD2VVW
InChIKey: QORVDGQLPPAFRS-XPSHAMGMSA-N

Note

  • A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.

Molecular Formula

  • C17-H21-N-O3.Br-H

Molecular Weight

  • 368.2688
 

Classification Codes

  • Cholinergic Agents
  • Treatment of Alzheimer's Disease (Cholinesterase Inhibitor)

Names and Synonyms

Name of Substance

  • Galantamine hydrobromide
  • Galantamine hydrobromide [USAN:USP]

Synonyms

  • 6H-Benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
  • EINECS 217-780-5
  • Galantamine hydrobromide
  • Galanthamine hydrobromide
  • Jilcon hydrobromide
  • Lycoremine hydrobromide
  • Nivalin
  • Nivaline
  • Nivaline (pharmaceutical)
  • Razadyne
  • Razadyne ER
  • Reminyl
  • UNII-MJ4PTD2VVW

Registry Numbers

CAS Registry Number

  • 1953-04-4

FDA UNII

  • MJ4PTD2VVW

System Generated Number

  • 0001953044

Structure Descriptors

InChI

1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChIKey

QORVDGQLPPAFRS-XPSHAMGMSA-N

Smiles

Br.COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24