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Substance Name: Fluazacort [USAN:INN]
RN: 19888-56-3
UNII: Y37GZ3VFSS
InChIKey: BYZCJOHDXLROEC-RBWIMXSLSA-N

Classification Codes

  • Anti-Inflammatory
  • Drug / Therapeutic Agent
  • Hormone

Molecular Formula

  • C25-H30-F-N-O6

Molecular Weight

  • 459.511
 
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Names and Synonyms

Name of Substance

  • Fluazacort
  • Fluazacort [USAN:INN]

Synonyms

  • 5'H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (5'beta,11beta)-
  • 9-Fluoro-11beta,21-dihydroxy-2'-methyl-5'betaH-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione 21-acetate
  • Azacortid
  • EINECS 243-400-2
  • Fluazacort
  • Fluazacort acetate
  • Fluazacort acetato
  • Fluazacort acetato [Spanish]
  • Fluazacortum
  • Fluazacortum [INN-Latin]
  • L 6400
  • L-6400
  • UNII-Y37GZ3VFSS

Systematic Names

  • 5'-beta-H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 9-fluoro-11-beta,21-dihydroxy-2'-methyl-, 21-acetate
  • 5'H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (5'beta,11beta)-
  • Fluazacort

Registry Numbers

CAS Registry Number

  • 19888-56-3

FDA UNII

  • Y37GZ3VFSS

System Generated Number

  • 0019888563

Structure Descriptors

InChI

1S/C25H30FNO6/c1-13-27-25(20(31)12-32-14(2)28)21(33-13)10-18-17-6-5-15-9-16(29)7-8-22(15,3)24(17,26)19(30)11-23(18,25)4/h7-9,17-19,21,30H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-,25+/m0/s1

InChIKey

BYZCJOHDXLROEC-RBWIMXSLSA-N

Smiles

CC(=O)OCC(=O)[C@@]12N=C(C)O[C@@H]1C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 54mg/kg (54mg/kg)   Medicamentos de Actualidad. Vol. 12, Pg. 396, 1976.
rat LD50 subcutaneous 580mg/kg (580mg/kg)   Medicamentos de Actualidad. Vol. 12, Pg. 396, 1976.