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Substance Name: Nirsevimab [USAN]
RN: 1989556-22-0
UNII: VRN8S9CW5V

Note

  • Monoclonal antibody to RSV with an extended half-life.

Molecular Formula

  • C6494-H10060-N1708-O2050-S46 (nonglycosylated)
 

Classification Codes

  • Prevention of Respiratory Syncytial Virus Infection
  • Treatment of Respiratory Syncytial Virus
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Names and Synonyms

Name of Substance

  • Nirsevimab [USAN]

Synonyms

  • Immunoglobulin G1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein F0 (protein F)); human monoclonal antibody; gamma1 heavy chain (1-456) (human VH (Homo sapiens IGHV1-69*01-(IGHD)-IGHJ4*01 (90.1%)) (8.8.19) (1-126) -Homo sapiens IGHG1*03 (CH2 M22>Y(261),S24>T(263),T26>E(265)) (127-456)) (229-214')-disulfide with kappa light chain (1'-214') (human V-KAPPA (Homo sapiens IGKV1-33*01-IGKJ4*01)(96%) (6.3.9) (1'-107') -Homo sapiens IGKC*01 (108'-214')), dimer (235-235'':238-238'')-bisdisulfide
  • MEDI8897
  • Nirsevimab
  • UNII-VRN8S9CW5V

Systematic Name

  • Immunoglobulin G1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal MEDI8897 gamma1-chain), disulfide with monoclonal MEDI8897 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 1989556-22-0

FDA UNII

  • VRN8S9CW5V

System Generated Number

  • 1989556220