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Substance Name: Memantine [INN:BAN]
RN: 19982-08-2
UNII: W8O17SJF3T
InChIKey: BUGYDGFZZOZRHP-UHFFFAOYSA-N

Note

  • AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.

Molecular Formula

  • C12-H21-N

Molecular Weight

  • 179.305
 

Classification Codes

  • Anti-Dyskinesia Agents
  • Antiparkinson Agents
  • Central Nervous System Agents
  • Dopamine Agents
  • Excitatory Amino Acid Agents
  • Excitatory Amino Acid Antagonists
  • N-Methyl-D-Asparate (NMDA) Antagonist
  • Neurotransmitter Agents

Names and Synonyms

Name of Substance

  • Memantine
  • Memantine [INN:BAN]

MeSH Heading

  • Memantine

Synonyms

  • 1,3-Dimethyl-5-adamantanamine
  • 1-Amino-3,5-dimethyladamantane
  • 3,5-Dimethyl-1-adamantylamine
  • 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
  • Alzantin
  • D 145
  • DMAA [Antiparkinson Agent]
  • DRG 0267
  • Ebixa
  • HSDB 7327
  • Memantina
  • Memantina [INN-Spanish]
  • Memantine
  • Memantinum
  • Memantinum [INN-Latin]
  • UNII-W8O17SJF3T

Systematic Names

  • 3,5-Dimethyl-1-adamantanamine
  • Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-

Registry Numbers

CAS Registry Number

  • 19982-08-2

FDA UNII

  • W8O17SJF3T

Other Registry Number

  • 51052-62-1

Related Registry Number

  • 41100-52-1 (Hydrochloride)

System Generated Number

  • 0019982082

Structure Descriptors

InChI

1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3

InChIKey

BUGYDGFZZOZRHP-UHFFFAOYSA-N

Smiles

C1[C@@]2(CC3(CC(C2)C[C@@]1(C3)C)N)C

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 258 deg C   EXP
log P (octanol-water) 3.28 (none)   EXP
Water Solubility 894 mg/L 25 EST
Vapor Pressure 0.036 mm Hg 25 EST
Henry's Law Constant 1.47E-05 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 3.34E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.