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Substance Name: Tenofovir Disoproxil
RN: 201341-05-1
UNII: F4YU4LON7I
InChIKey: JFVZFKDSXNQEJW-CQSZACIVSA-N

Note

  • /Tenofovir/ An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

Molecular Formula

  • C19-H30-N5-O10-P

Molecular Weight

  • 519.445
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Reverse Transcriptase Inhibitors

Names and Synonyms

Name of Substance

  • Tenofovir Disoproxil

Synonyms

  • Bis(POC)PMPA
  • PMPA prodrug
  • UNII-F4YU4LON7I
  • Viread

Systematic Name

  • 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine

Registry Numbers

CAS Registry Number

  • 201341-05-1

FDA UNII

  • F4YU4LON7I

System Generated Number

  • 0201341051

Structure Descriptors

InChI

1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m1/s1

InChIKey

JFVZFKDSXNQEJW-CQSZACIVSA-N

Smiles

CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)OCOC(=O)OC(C)C