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Substance Name: Mepiprazole dihydrochloride
RN: 20344-15-4
UNII: TN5WJ92YGP
InChIKey: FOZDCFRVHJVSIY-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C16-H21-Cl-N4.2Cl-H

Molecular Weight

  • 377.745
 
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Names and Synonyms

Name of Substance

  • Mepiprazole dihydrochloride

Synonyms

  • H 4007
  • Mepiprazole dihydrochloride
  • Mepiprazole HCl
  • Mepiprazole hydrochloride
  • Piperazine, 1-(3-chlorophenyl)-4-(2-(5-methyl-1H-pyrazol-3-yl)ethyl)-, dihydrochloride
  • Quiadon
  • UNII-TN5WJ92YGP

Systematic Name

  • Piperazine, 1-(m-chlorophenyl)-4-(2-(5-methylpyrazol-3-yl)ethyl)-, dihydrochloride

Registry Numbers

CAS Registry Number

  • 20344-15-4

FDA UNII

  • TN5WJ92YGP

Related Registry Number

  • 20326-12-9 (Parent)

System Generated Number

  • 0020344154

Molecular Formulas

Molecular Formula

  • C16-H21-Cl-N4.2Cl-H

Molecular Formula Fragments

  • C16-H21-Cl-N4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C16H21ClN4.2ClH/c1-13-11-15(19-18-13)5-6-20-7-9-21(10-8-20)16-4-2-3-14(17)12-16;;/h2-4,11-12H,5-10H2,1H3,(H,18,19);2*1H

InChIKey

FOZDCFRVHJVSIY-UHFFFAOYSA-N

Smiles

N1(CCN(CCc2n[nH]c(c2)C)CC1)c1cc(ccc1)Cl.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 110mg/kg (110mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.
mouse LD50 oral 310mg/kg (310mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.
mouse LD50 subcutaneous 440mg/kg (440mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.
rat LD50 intravenous 93mg/kg (93mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.
rat LD50 oral 570mg/kg (570mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.
rat LD50 subcutaneous 435mg/kg (435mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 336, 1973.