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Substance Name: Buthiazide [USAN]
RN: 2043-38-1
UNII: W00SSD35VW
InChIKey: HGBFRHCDYZJRAO-UHFFFAOYSA-N

Note

  • 3-isobutyl analog of hydrochlorothiazide.

Molecular Formula

  • C11-H16-Cl-N3-O4-S2

Molecular Weight

  • 353.8494
 

Classification Codes

  • Antihypertensive
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Diuretic
  • Diuretics
  • Natriuretic Agents
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Names and Synonyms

Name of Substance

  • Buthiazide
  • Buthiazide [USAN]
  • Butizide [INN]

Synonyms

  • 6-Chloro-3,4-dihydro-3-isobutyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • Buthiazide
  • Butizida
  • Butizida [INN-Spanish]
  • Butizide
  • Butizidum
  • Butizidum [INN-Latin]
  • EINECS 218-048-8
  • Eunephran
  • S 3500
  • Saltucin
  • SU 6187
  • UNII-W00SSD35VW

Systematic Names

  • 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(2-methylpropyl)-, 1,1-dioxide
  • 6-Chloro-3,4-dihydro-3-isobutyl-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
  • Butizide

Registry Numbers

CAS Registry Number

  • 2043-38-1

FDA UNII

  • W00SSD35VW

System Generated Number

  • 0002043381

Structure Descriptors

InChI

1S/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17)

InChIKey

HGBFRHCDYZJRAO-UHFFFAOYSA-N

Smiles

CC(C)CC1Nc2cc(Cl)c(cc2S(=O)(=O)N1)S(=O)(=O)N

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 221.5 deg C   EXP
log P (octanol-water) 1.200 (none)   EST
Atmospheric OH Rate Constant 2.12E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.